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Audio-Visual Stimulation and the hypothalamic-pituitary-adrenal axis The adrenal axis (hypothalamic-pituitary-adrenal axis) is a crucial neuroendocrine system referring to a complex set of interactions and feedback loops between the hypothalamus, pituitary, and adrenal glands. This system regulates the body’s response to stress, immune function, energy expenditure, mood, emotions, and libido. Components of the HPA Axis Hypothalamus: This small region at the base of the brain detects stress and releases corticotropin-releasing hormone (CRH). It plays a key...